Copolymerization of epoxides with cyclic anhydrides catalyzed by dinuclear cobalt complexes

• Yo Hiranoi and
• Koji Nakano

Beilstein J. Org. Chem. 2018, 14, 2779–2788, doi:10.3762/bjoc.14.255

• turnover frequencies ever reported. A variety of epoxides and CAs were also found to be copolymerized successfully by the dinuclear cobalt complex with a high catalytic activity. Keywords: cobalt; copolymerization; cyclic anhydrides; epoxides; polyesters; Introduction Aliphatic polyesters have received

An economical and safe procedure to synthesize 2-hydroxy-4-pentynoic acid: A precursor towards ‘clickable’ biodegradable polylactide

• Quanxuan Zhang,
• Hong Ren and
• Gregory L. Baker

Beilstein J. Org. Chem. 2014, 10, 1365–1371, doi:10.3762/bjoc.10.139

• Aliphatic polyesters, in particular polylactide (PLA), are now widely used for biomedical applications, such as surgery sutures [1], implants for bone fixation [2], drug delivery vehicles [3][4] and tissue engineering scaffolds [5] because of their excellent biocompatibility, biodegradability and mechanical

1-n-Butyl-3-methylimidazolium-2-carboxylate: a versatile precatalyst for the ring-opening polymerization of ε-caprolactone and rac-lactide under solvent-free conditions

• Astrid Hoppe,
• Faten Sadaka,
• Claire-Hélène Brachais,
• Gilles Boni,
• Jean-Pierre Couvercelle and
• Laurent Plasseraud

Beilstein J. Org. Chem. 2013, 9, 647–654, doi:10.3762/bjoc.9.73

• under vacuo (method A) or by addition of NaBPh4 (method B). Possible catalytic and deactivation mechanisms are proposed. Keywords: aliphatic polyesters; green polymerization reaction; imidazolium-2-carboxylates; N-heterocarbene precursor; organocatalysis; Introduction Poly(ε-caprolactone) (PCL) and

• polylactic acid (PLA) are biologically relevant aliphatic polyesters. Their applications vary, due to their compatibility with other polymers and their biodegradability, from packaging to pharmaceutics and medicine [1][2][3][4][5][6]. PCL serves for instance as a scaffold for tissue engineering [7][8] and as

Poly(glycolide) multi-arm star polymers: Improved solubility via limited arm length

• Florian K. Wolf,
• Anna M. Fischer and
• Holger Frey

Beilstein J. Org. Chem. 2010, 6, No. 67, doi:10.3762/bjoc.6.67

• compared to the homopolymer PGA should lead to simplified processing conditions. The findings contribute to broadening the range of biomedical applications of PGA. Keywords: block copolymer; hyperbranched; PGA; polyester; polyglycerol; poly(glycolide); star polymer; Introduction Linear aliphatic

• polyesters such as polylactic acid (PLA) and poly(ε-caprolactone) [1] are of great interest due to their biodegradability, biocompatibility and permeability for many drugs. In contrast, poly(glycolic acid) (PGA) is scarcely used because of its high degree of crystallinity and its insolubility in all common